Unani Zarambaad Siddha Tamil Kichhilikkizhangu

Action ► Carminative, stomachic, gastrointestinal stimulant, diuretic, expectorant, demulcent, rubefacient. Used in flatulence and dyspepsia. Fresh root is used for checking lecorrhoeal discharge; also for blood purification. Zedoary's effect on digestive organs is similar to ginger but milder.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicated the use of the rhizome in goiter.

The rhizomes are a source of Shoti Starch, used as a food for babies and convalescents, recovering from chronic stomatitis. It is cooling and demulcent.

Zedoary, dried rhizomes, contains a number of terpenoids, including curcumene, curcumenone, curdione, curcumenol. Curzerenone, furanoger-menone, germacrone, germacrone epoxide; a volatile oil (1.0-1.5%) resembling ginger oil, and starch (50%).

Zedoary is thought to stimulate bile production (due to sesquiterpene ke-tones) and gall bladder emptying (due to cucuminoid constituents).

The sesquiterpenes, germacrone, germacrone epoxide, curzerenone and curcumenol showed CNS depressant properties. Curzerenone also showed a potent protective effect against induced lesions in rats. Both curz-erenone and curcumenol showed a moderate analgesic action.

The terpenoid furanogermenone exhibits antiallergic activity. (Powdered zedoary, mixed with fructose, is used as an antiallergant in Japan.)

Cyamopsis tetragonoloba (Linn.) Taub. 189

Curcumenol and curdione are shown to possess tumour-inhibiting property. The rhizome is used in China for extradural haematomas and certain types of tumours. It has been reported in China that zedoary reduced cervical cancer and increased the effects of chemotherapy and radiotherapy.

The volatile oil of zedoary exhibits antimicrobial and antifungal activity. The antifungal constituent of the oil has been reported as methyl-p-methoxy-cinnamate.

Dosage ► Dried rhizome—1-3 g powder. (API Vol. IV.)

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