Synonym S officinale Nees and Eberm

S. variifolium Kuntze.

Saussurea affinis Spreng. ex DC. 585

Family ► Lauraceae.

Habitat ► Canada to Florida. Dried roots of S. albidum are imported into India.

Unani ► Sassafras.

Action ► Root—used earlier for rheumatism, gout, kidney complaints and skin diseases.

Safrole is the main constituent of the volatile oil (80-90%), in addition to condensed tannins, resin, cinnam-ic acid derivatives. Safrole and its metabolite, L-hydroxysafrole are both neuro- and hepatotoxic (carcinogenic in animals). Its internal use is no more advised. Safrole-free extracts are ineffective.

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