Action ► Bark—antipyretic (particularly prescribed in malaria), bitter tonic in general debility, astringent (used for diarrhoea and dysentery); used as a gargle in stomatitis, applied to rheumatic swellings. The bark is much inferior to cinchona bark, but a good substitute for oak bark.
The plant contains mainly tetra-nor-triterpenoids and flavonoids. The heartwood gave febrifugine A and B, febrinins A and B; flavonoids— naringenin, quercetin, myricetin and dehydromyricetin. The Root heart-wood yielded sitosterol, obtusifoliol, syringetin and dihydrosyringetin. The bark contains tetranor-triterpenoids with modified furan ring.
Petroleum ether extract of the bark yielded a steroid, methyl angolensate, ether extract yielded a steroid glyco-side.
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