Action ► Flowers—stomachic, aperient, anti-inflammatory. Leaves— prescribed in migraine (as circulatory stimulant). Uses same as those of chamomile.
The flowers contain daucosterol, cumambrin-A, glyceryl-l-monobehe-nate and palmitic acid. The flowers also contain chrysanthemol which showed strong anti-inflammatory activity in mice. The flavones, apigenin and lu-teolin, are reported to exhibit marked antitumour activity.
Flowers yield an essential oil containing camphor (16.0%), trans-cara-ne-trans-2-ol (15.0%), bornyl acetate (12.0%) and sabinene (7%).
A related species C. parthenium (Linn.) Berhh., Feverfew, synonym Tanacetum parthenium, used for the management of migraine in Western herbal, is found in Jammu and Kashmir. The plant extracts have a powerful and prostaglandin-independent inhibitory effect on the secretion of granule content by leucocytes and platelets. The inhibition of the agonist-induced serotonins release by platelets could be accounted for the benefit in migraine. The compound responsible for the anti-secretory activity has been identified as sesquiterpene alpha-methylene-gamma-lactone derivatives; partheno-lide being the main constituent of the lactones. (Two fresh or frozen leaves a day are chewed or capsules or pills containing 86 mg of the leaf material is taken for migraine. Fresh leaves may cause mouth sores.)
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