Action ► Antispasmodic, carminative, antiputrescent, antidiarrhoeal, antiemetic, antimicrobial, mild analgesic. Used for flatulent dyspepsia, colic, irritable bowel, diverticulosis; also for influenza and colds.
Key application ► In loss of appetite, dyspeptic complaints such as mild spasma of gastrointestinal tract, bloating, flatulence. (German Commission E, The British Herbal Pharmacopoeia, ESCOP.)
The bark yields an essential oil containing cinnamaldehyde (82.2%) and eugenol (1.5%) as major constituents.
Cinnamaldehyde is a weak CNS stimulant at low doses and a depressant at high doses and has spasmolytic activity. It is hypotensive, hypogly-caemic and increases peripheral blood flow; it reduces platelet aggregability by inhibiting both cyclooxygenase and lipoxygenase pathways of arachidonic acid metabolism.
Aqueous extract of the bark shows significant antiallergic activity in guinea pig. Diterpenes (Cinncassi-ols) are thought to be responsible for atleast some of the antiallergic effects.
The herb inhibited ulcers induced by ethanol, also ulcers induced by phenylbutazone; failed to prevent ulcers induced by indomethacin. (Planta Med 1989, 55(3), 245-248.)
The extract, when administered orally to rats with nephritis, prevents the increase of protein level in urine.
The bark markedly reduces blood pressure in experimental rats; exhibits tranquilizing effect and is used as an antiepileptic and sedative agent in drugs ofTCM.
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