Siddha Tamil Akkiraakaaram

Anamirta cocculus (Linn.) Wight and Arn. 47

Action ► Stimulant, cordial, rubefa-cient.A gargle of infusion is prescribed for relaxed vulva. Root— used for toothache, rheumatic and neuralgic affections and rhinitis. Roots, along with the root of Witha-nia somnífera and Vitis vinifera, are used in epilepsy.

Along with other therapeutic applications, Ayurvedic Pharmacopoeia of India indicates the use of the root in sciatica, paralysis, hemiplegia and amenorrhoea.

The root contains anacycline, isobu-tylamide, inulin and a trace ofessential oil.

The local anaesthetic activity of the alcoholic (2%) extract of the root was found to be comparable to that of xy-locaine hydrochloride (2%) in dental patients.

Use of the drug in patients with insulin-dependent diabetes mellitus reduces the dose of insulin. It decreased the plasma glucose and serum cholesterol levels after oral administration for 3-6 weeks. (The plant is mixed with Helleborus nigar in a ratio of 1:3.) The plant extract inhibited tobacco-induced mutagenesis by 47.5% at a concentration of 1 mg/plate.

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