Action ► Pulp of ripe fruit—astringent; used in chronic dysentery. Flowers, fruit and bark—astringent. Bark—given for promoting fertility in women. Seeds—purgative. The leaves contain sterols, reducing sugars and tannins; roots, a steroidal saponin; stem bark, spinasterol and taraxerol; flowers, D-mannitol, beta-sitosterol and beta-sitosterol-D-glycoside; seeds, pentacyclic triterpene acids, mimusopic and mimusopsic acids.
Essential oil obtained from the plant is reported to be mycotoxic. Antimicrobial activity of the root extract has
been reported. Saponins isolated from the seeds have been found to effect the cardiovascular activity in dogs and haemolytic activity in human beings. Spasmolytic activity in isolated ileum of guinea-pigs has also been recorded. Saponins from seeds also showed spermicidal activity.
Dosage ► Seed, bark—10-20 g paste; 50-100 ml decoction. (CCRAS.)
Two Mirabilis jalapa antimicrobial proteins, Mj-AMP-1 and Mj-AMP-2, isolated from seeds, showed broad spectrum antifungal actvity involving a number of pathogenic fungi.
Miraxanthins I, II, III and IV, indi-caxanthin and vulgaxanthin have been isolated from flowers.
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