Action ► Carminative, astringent, anti-inflammatory, antirheumat-ic, hepatoprotective, diuretic, antipyretic, analgesic, hypoten-sive, emmenagogue and nervine tonic.
Used for intestinal problems, indigestion, sprue, diarrhoea, dysentery, vomiting and fever; also as a hypoc-holesterolaemic drug and in obesity.
Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicated the use of the rhizome in rheumatism, inflammations, dysuria, puerperal diseases and obesity.
The tuber is rich in Cu, Fe, Mg and Ni. Beta-sitosterol, isolated from the tubers, exhibits significant anti-inflammatory activity against carra-geenan- and cotton pellet-induced oedema in rats; the activity is comparable to hydrocortisone and phenyl-
butazone when administered intraperi-toneally.
The alcoholic and aqueous extracts of the tubers possess lipolytic action and reduce obesity by releasing enhanced concentrations of biogenic amines from nerve terminals of the brain which suppress the appetite centre. Presence of eudalne group of ses-quiterpenic compounds of sesquiter-pene alcohol, isocyperol is said to play an important role in lipid metabolism.
An alcoholic extract of the plant exhibits liver-protective activity against CCL4-induced liver damage in mice.
Methanolic extract of the plant stimulates the production of melanin in cultured melanocytes. (Plant extract is used in preparations used for pigmentation of skin and hair, also in suntan gels.)
Aqueous-alcoholic extract of the tuber exhibited hypotensive, diuretic, antipyretic and analgesic activities. These are attributed to a triterpenoid.
The essential oil (0.5-0.9%) from the tubers contains mainly sesquiterpenes.
C. platystilis Br. is equated with Kaivarta-mustaka.
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