Action ► Leaf and seed—purgative. Leaf—antidermatosis. Bark— emmenagogue. Seed—emetic. Seed fatty oil—used in paralytic affections, also in skin diseases.
The leaves contain triterpenes, a tri-hydroxy ketone and corresponding diosphenol. The root contains the diterpenes, jatropholone A and jat-rophatrione. A tumour-inhibitor ma-crocyclic diterpene, jatrophone, has been isolated from roots.
The seeds contain phorbol derivatives, jatropholones A and B, hydroxy-jatrophone and hydroxyisojatrophone.
Hot water extract of the plant exhibits antimalarial activity against Plasmodium falciparum.
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