Action ► Rhizome—carminative, spasmolytic, hepatoprotective, anti-inflammatory, antiemetic, antidiarrhoeal, analgesic, expectorant, antiasthmatic, emmenagogue, hypoglycaemic, hypotensive, antimicrobial, anthelmintic, insect-repellent.
The rhizome shows hypotensive effect in dogs at low doses, lowers blood pressure in high doses.
Hedyotis corymbosa (Linn.) Lam.
EtOH (50%) extract—anti-inflammatory and hypoglycaemic; gave encouraging results in tropical pulmonary eosinophilia in clinical studies. Alcoholic extract of the plant—vasodilator, mild hypotensive and antiseptic in animals. Essential oil from rhizome—mild tranquilizer in male albino rats; antimicrobial.
Rhizome gave sitosterol and its glu-coside, a furanoid diterpene—hedy-chenone and 7-hydroxyhedychenone. The essential oil contains cineole, gamma-terpinene, limonene, beta-phellandrene, p-cymene, linalool and beta-terpineol as major constituents.
The oil inhibits the growth of several fungi. The ethanol (95%) extract showed antibacterial activity. The 50% extract showed antimalarial activity in vitro against Plasmodium berghei strain.
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