Action ► Leaf and root—astringent, bechic, antiasthmatic, anti-inflammatory, hypothermic, diuretic. Seed—cathartic, diuretic, haemostatic.
Key application ► Internally, for catarrhs of the respiratory tract and inflammatory alterations of the oral and pharyngeal mucosa; externally for inflammatory reactions of the skin. (German Commission E, ESCOP.)
Globularin and methyl ester of de-sacetyl asperulosidic acid were isolated from the plant along with cat-apol. A crude mucilage, isolated from the leaves, contains L-arabinose 26.0, D-galactose 35.8, D-glucose 21.9, D-mannose 4.6, L-rhamnose 4.6 and uronic acid 6.9%. Alpha-D-glucan was separated from this mucilage.
Leaves gave aucubin and esculetin, in addition to polysaccharides. The whole plant yielded rhamnosidoglyco-side of caffeic acid. Seeds contain 1.1% aucubin. Aucubin exhibits antibacterial activity. Hepatoprotective effect is also attributed to the aucubin content.
Alcoholic extract of young leaves exhibit antibacterial action against Streptococcus betahaemolyticus, Micrococcus pyogenes var. aureus and Bacillus subtilis, thus confirming their wound-healing properties.
498 Plantago major Linn.
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