Ayurvedic ► Karanja.
Siddha/Tamil ► Pungam.
Action ► Oil—applied in scabies, herpes, leucoderma and other cutaneous diseases; over chest in pneumonia and cold; also used
internally as cholagogue in sluggish liver. Leaves—juice is prescribed in flatulence, dyspepsia, diarrhoea and cough. An infusion is given for leprosy and gonorrhoea. Root— a paste is used in scrofulous enlargements; juice is used for cleaning foul ulcers and closing fistulous sores. Stem bark—given internally in bleeding piles. Rind of pod and seed—prescribed in bronchitis and whooping cough. Leaf and seed—antileprotic. Leaf and seed oil—antirheumatic.
The tree is rich in flavonoids and related compounds. These include simple flavones, furanoflavonoids, chro-menoflavones, chromenochalcones, coumarones, flavone glucosides, sterols, triterpenes and a modified phenylalanine dipeptide. Seeds and seed oil gave karanjin, pongamol, pongapin and kanjone.
The aqueous extract of stem bark shows significant sedative and antipyretic effects in rats, and antispas-modic effect in vitro on smooth muscles.
In Indonesia, a decoction ofthe bark is drunk after child birth.
The aqueous extract of seeds showed significant antiviral activity against herpes simplex viruses HSV-1 and 2 cell lines experimentally. Albino rats, treated with the aqueous extract of seeds, recovered faster from induced infection and skin-burn than the untreated ones.
Dosage ► Seed—250 mg powder; 510 g for decoction. (API, Vol. I.)
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