Hook. ex Stocks
Synonym ► Commiphora mukul (Hook. ex Stocks) Engl. C. wightii (Arn.) Bhandari.
Family ► Burseraceae.
Habitat ► Rajasthan, Madhya Pradesh, Assam, Andhra Pradesh, Karnataka.
English ► Indian Bdellium, Gum Guggul.
Ayurvedic ► Guggul, Devadhoop, Kaushika, Pur, Mahishaaksha, Palankash, Kumbha, Uluukhala.
Unani ► Muqallal yahood, Muql, Bu-e-Jahudaan
Siddha/Tamil ► Erumaikan Kungiliyam.
Action ► Oleo-gum-resin—used for reducing obesity and in rheumatoid arthritis, osteoarthritis, sciatica.
Key application ► In the treatment of hyperlipidemia, hypercholestero-laemia and obesity. (WHO.)
Guggulipid is hypocholesteremic. Guggul resin contains steroids—gug-glsterones Z and E, guggulsterols IV, diterpenoids; volatile oil, including other constituents, contains a terpene hydrocarbon cembrene A. E- and Z-guggulsterones are characteristic constituents, which distinguish C. mukul from other Commiphore sp.
Guggul resin increases catechola-mine biosynthesis and activity in cholesterol-fed rabbits, inhibits platelet aggregation, exhibits anti-inflammatory activity and appears to activate the thyroid gland in rats and chicken. Z-guggulsterone may increase uptake of iodine by thyroid gland and increase oxygen uptake in liver and bicep tissues. (Planta Med 1984,1, 78-80.)
The gum is also used in hemiplegia and atherosclerotic disorders; as a gargle in pyrrhoea aveolaris, chronic tonsilitis and pharyngitis. Fumes are recommended in hay fever, chronic bronchitis and nasal catarrh.
Oleo-gum resin of Balsamodendron caudatum is also equated with Guggul in Siddha medicine.
Dosage ► Oleo-gum-resin—2-4 g (API Vol. I.) 500 mg to 1 g (CCRAS.)
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