Family ► Compositae; Asteraceae.
Habitat ► The western Himalayas from Kashmir to Kumaon.
English ► Wormseed, Santonica.
Ayurvedic ► Chauhaara, Kirmaani Yavaani, Chuhaari Ajawaayin; not related to Ajawaayin.
Unani ► Dirmanah, Kirmaalaa, Afsanteen-ul-bahar. (Dirmanah Turki is equated with A. stechmani-ana Besser.)
Folk ► Kirmaani Ajawaayin, Kirmaani-owaa, Kirmaani-ajmo.
Action ► Deobstructant, stomachic, anthelmintic (effective against roundworms), antifungal.
A decoction of the fresh plant is given in cases of intermittent and remittent fever.
A. maritima var. thomsoniana C. B. Clarke is a santonin-yielding var.; A. maritima var. fragrans (Willd.) Ledeb. is a non-santonin var.
Immature flowerheads and leaves contain santonin. Roots, stems and twigs are devoid of santonin. Santonin, a sesquiterpene lactone, is used for the treatment of ascaris and oxyuris infections. Large doses (0.3 g is adults and 0.06 in children) are toxic.
Beta-santonin is less anthelmintic in action than santonin; pseudosantonin is devoid of anthelmintic property.
Studies is albino mice revealed that santonin had no androgenic, estro-genic, antiestrogenic, progestational and antiprogestational effects.
Santonin is toxic at 60 mg in children; 200 mg in adults. (Francis Brinker.)
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