Alangium begoniaefolium

Family ► Alangiaceae.

Habitat ► The plains and foothills, up to an altitude of 2,100 m.

Action ► Bark and roots—sedative, anthelmintic.

A triterpenoid was responsible for the sedative effect on motor activity of rat brain.

Chloroform extract of the drug, which was devoid of anabasine, exhibited prominent sedative effect in rat. It significantly decreased concentration of norepinephrine in cortex, of dopamine and serotonin (5-HT) in brain stem, but increased concentration of 5-HT in cortex.

hypoglycaemic. Fruits—acidic, astringent, laxative and refrigerant. Used in haemorrhages, strangury and consumption. The bark is used as a substitute for Cephaelis ipecacuanha. It is a rich source of alkaloids structurally related to ipecac alkaloids (emetin).

The bark contains the alkaloid alan-gine which shows a selective action of the parasympathetic mechanism, the action being more marked on gastrointestinal tract. The root extract shows hypotensive action. Flowers contain deoxytubulosine, a potent antiplatelet aggregation component, which has a strong binding with DNA.

The plant extract possesses antineo-plastic properties.

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